In a study of 162 cats in Italy Pennisi et al (1999) demonstrated an isolation rate of 32% in cats with a history of URTD whereas in cats with no history of URTD, the isolation rate was 13% with significant statistical difference between the 2 groups: History of URTD | Number of cats tested/ positive (% positive) | + | 22/68 (32%) | - | 9/67 (13%) | Isolation rate of B. bronchiseptica in cats with or without history of URTD (Pennisi et al 1999) |